MYCN and neuroblastoma: To gain insight into the transcriptional changes induced by I-BET726 in neuroblastoma, MYCN-amplified (CHP-212) and non-MYCN-amplified (SK–N–SH) cell lines were treated with 100 nM or 1 μM I-BET726 for 16 hours and profiled by Illumina microarrays.