PML and acute myeloid leukemia: Acute promyelocytic leukaemia (APML) constitutes 5–10% of acute myeloid leukaemia (AML) and is characterised by a reciprocal translocation between chromosomes 15 and 17 [1], leading to the fusion of retinoic acid receptor alpha (RARA) gene on chromosome 17 at q21 and promyelocytic leukaemia (PML) gene on chromosome 15 at q22.