The closest human homologue to Ipr1 is Sp110, and mutations in Sp110 have been associated with hepatic veno-occlusive disease with immunodeficiency (VODI) [7], [8]; however, the role of Sp110 in human tuberculosis is still being debated [9], [10], [11]. This evidence concerns the gene SP110 and hepatic veno-occlusive disease.