PRDX1 and cancer: A high level of Prdx1 expression was significantly correlated with poor overall survival in most reported cancers, but inversely reduced Prdx1 expression was correlated with reduced overall survival and poor clinical outcome in cholangiocarcinoma, suggesting that Prdx1 is a valuable prognostic marker in predicting the outcome, recurrence and overall survival in patients with certain types of tumors.