The present study revealed that there was a high level of expression of Prdx1 in the liver cancer cell line HepG2, breast, ovarian and lung cancer cell lines (SKBR3, SKOV3 and A549), and relatively weak expression in another type of liver cancer cell line (SUN449) and in laryngeal cancer (Hep2), acute lymphoblastic leukemia (MOLT-4) and lymphoma leukemia (KOPN63) cell lines. This evidence concerns the gene PRDX1 and liver cancer.