PRDX1 and cholangiocarcinoma: Prdx1 expression was increased in lung (10,11), liver (12), gallbladder (13), bladder (14), prostate (15) and ovarian cancer (16,26), and a high level of Prdx1 expression was significantly correlated with tumor grade and clinical stage in some types of tumors such as non-small cell lung cancer (NSCLC), gallbladder cancer and cholangiocarcinoma (10,12,13), but there was no correlation noted in ovarian carcinoma (16).