HP and Alzheimer disease: Although the observed changes may be merely epiphenomenal to the pathological processes occurring in the AD neocortex and Hp, the morphological and immunocytochemical differences between cerebral and cerebellar cortices of AD patients may nonetheless give insights into the molecular factors involved in the development of the neuropathological lesions of the AD brain.16 Consequently, more attention has also been given to this brain area in recent years, though with little focus at the molecular level.17, 18, 19, 20, 21, 22, 23, 24