These two pathways were for the 53 genes for ALL ASD versus TD comparison and included: (1) the Nrf2-mediated oxidative stress response (SOD2, CAT, PRDX1, PIK3C3, DNAJC17, and MGST3); and (2) the superoxide radical degradation (SOD2, CAT). This evidence concerns the gene CAT and thanatophoric dysplasia.