Several miRNAs have been identified which target MET oncogene, including miR-34a, miR-199, miR-206, and miR-1 that could be challenged in therapies for silencing MET. We have recently observed that miR-1 is downregulated in CRC with respect to matched normal tissues and we have demonstrated that this miRNA can downregulate MET expression in vitro CRC models. Here, MET is linked to colorectal carcinoma.