P values to include the excluded covariates in the final model were >0.17 (P53, p = 0.57; MGMT, p = 0.24; EGFR, p = 0.45; tumor size, p = 0.51; operation, p = 0.84; multifocal vs. single lesion, p = 0.17). The gene discussed is TP53; the disease is neoplasm.