The higher prevalence of lung metastasis (in the absence of liver metastases) in HER2-amplified tumours was significantly different to that of non-HER2-amplified tumours (P = 0.0022; Table 3), as was the rate of recurrence at any site without liver metastases (P = 0.0028; Table 3). Here, ERBB2 is linked to neoplasm.