CASP7 and chronic myelogenous leukemia, BCR-ABL1 positive: In CML-T1 cells, both used caspase inhibitors were able to effectively reduce caspase activation (Figure 3) causing 40% (z-VAD-fmk) and 60% (Q-VD-OPh) attenuation of active caspase-7 fragment, respectively, and 85% (z-VAD-fmk), respectively, complete (Q-VD-OPh) inhibition of active caspase-3 fragment.