CYCS and liver cancer: The ethanolic extract of BR rhizomes might contain active compounds such as the chalcone Boesenbergin A [47] and the sesquiterpene zerumbone [48] which were reported recently to induce apoptosis of liver cancer cells HepG2 through the release of cytochrome C and the formation of caspase-3 modifying the necrotic effect due to TAA intoxication to apoptosis.