IL1RN and gastric carcinoma: In their reports, El-Omar et al. (2000, 2001) demonstrated that the proinflammatory genotype (IL1B–511T, IL1B–31C and IL1RN*2) of the IL1 gene occurs together with the increased risk of gastric carcinoma as well as its probable precursors of atrophic gastric inflammation and hypochlorhydria in the case of Polish and Scottish populations.