Stable transfections of gefitinib resistant NSCLC cells with green fluorescent protein (GFP)-lentivirus constructs containing either full-length miRNAs or anti-miRNAs demonstrated that overexpression (miR-103 and miR-203) or knock down (miR-221 and -30c) of miRNAs differentially regulated by EGFR and Met TKRs could restore gefitinib sensitivity in vitro and in vivo [52]. Here, EGFR is linked to non-small cell lung carcinoma.