In actively demyelinating lesions, 17 of 24 (70.8%) lesions were classified as pattern A or B, 15 of 17 (88.0%) chronic active lesions showed pattern A or B and all 10 chronic inactive lesions were pattern A or B. Thus, all MS cases had pattern A or B lesions in terms of oligodendrocytic Cx32 and Cx47 expression. Here, GJB1 is linked to myeloid sarcoma.