Evseenko et al. showed that inhibition of BCRP activity by a BCRP-specific inhibitor Ko143 increased cytokine-induced apoptosis in primary trophoblasts and BeWo cells, and BCRP expression in placenta from pregnancies with idiopathic fetal growth restriction was significantly lower than that from normal pregnancies [56,57]. Here, ABCG2 is linked to fetal growth restriction.