Although genotype associations with breast cancer risk differed in strength according to self-reported race, no SNP by race interactions were statistically significant except for CXCL5-rs425535 and CRP-rs1205 among premenopausal women (P for interaction=0.007 and 0.01, respectively), and IL1B-rs1143627 and NOD2-rs2066842 among postmenopausal women (P for interaction=0.04, 0.04, respectively). This evidence concerns the gene IL1B and breast cancer.