TP53 and Ewing sarcoma: On the other hand, some researchers have reported that FGF2 can suppress proliferation by a variety of mechanisms, such as apoptosis in chondrocytes [10], p53-independent cell death in Ewing’s sarcoma tumors [11], [12], G1 arrest in MCF-7 human breast cancer cells, rat chondrosarcoma and pituitary lactotroph GH4 cells [13]–[16] and G2 arrest in a human neuroepithelioma cell line [17].