Previously, we reported an association between childhood ALL risk and the DP1 supertype of HLA-DPB1 (comprised of HLA-DPB1 alleles 01:01, 05:01, 50: 01) [12], a class II gene located about 55 kb from the associated rs9296068 SNP. The gene discussed is HLA-DPB1; the disease is acute lymphoblastic leukemia.