Because of the distribution of Anxa1 mRNA and FoxM1 mRNA expression in all glioblastoma did not accord with normal distribution, ROC curve was made based on the relative level of Anxa1or FoxM1 and overall survival status of human glioblastoma patients and group the all patients into low Anxa1 expression group (Anxa1low) and high Anxa1 expression group (Anxa1high), and low FoxM1 expression group (FoxM1low) and high FoxM1 expression group (FoxM1high). The gene discussed is ANXA1; the disease is glioblastoma.