To provide direct evidence that FoxM1 affect the angiogenic phenotype by regulating Anxa1 of glioma cells, we determined the angiogenic ability of the U-87MG-RNAi-Anxa1 and SW1088-FoxM1-RNAi cells using an endothelial cell tube formation assay. The gene discussed is FOXM1; the disease is glioma.