According to the data from immunoblotting and qPCR assays, E-cadherin expression was decreased in MEK-overexpressing OA (25 μg/mL, 50 μM)-treated U-87 MG glioma cells while there was no difference in its expression between MEK-overexpressing and control cells without OA treatments (Fig. 4d and 4e). The gene discussed is CDH1; the disease is central nervous system cancer.