FOS and cancer: In fact, many of the DE TFs dysregulated in the UC-stimulus-functions have been reported to function as a tumor promoter in inflammation-associated cancer, including all of the seven TFs shown in Figure 2B, which were FOSL1 [45], ETS1 [46], FOS [47], HIF1A [48], RELA [49], NFE2L2 [50] and HNF1A [51].