Examples of genes amplified on DMs include MYCN in neuroblastoma [12], C-MYC in colon cancer cells [13], EGFR in gliomas [14], and eIF-5A2 in ovarian cancer cells [15], and all of which when lost via DMs contributes to reversal of the cancer phenotype [12], [13], [14], [16]. Here, MYCN is linked to cancer.