Despite the wide variation in vascular expression of the receptors (28–92%), for all three RTKs, a positive tumour vasculature conferred a better overall survival compared with cases whose vessels were negative (p = 0.008 PDGFRA, p = 0.0012 KIT, p = 0.015 VEGFR2, log-rank test) (Figure 5C). Here, KDR is linked to neoplasm.