In addition to IFN-γ, TNF-α, cerebral and ocular mRNA levels of IL-6, NOS2 and IL-10 are increased in the brain and eye of mice infected with T. gondii, and these molecules promote protection against toxoplasmosis while in the case of IL-10, this cytokine modulates susceptibility to disease [25]–. Here, NOS2 is linked to toxoplasmosis.