Upon the present results, the expression of DLC1 and PAI-1 were closely related with the metastasis and invasion of ovarian carcinoma, both DLC1 and PAI-1could be used to assess the prognosis respectively, but only the combination of DLC1 and PAI-1 could serve as an independent prognostic factor of ovarian carcinoma. This evidence concerns the gene SERPINE1 and ovarian carcinoma.