Although the down-regulation of CD14, CD63, CD4, and CD38 among the CN good outcome group of HL patients was similar to normal controls, CD8 and CD19 were significantly down-regulated (CD8 by −125-fold and CD19 by −19085-fold) in the good outcome CN patients compared to normal samples (Figure 5B). This evidence concerns the gene CD38 and Hodgkins lymphoma.