POU5F1 and neoplasm: As shown in Table 2, the positive rates of PSCA and Oct-4 were significantly lower in the cases of well-differentiation, with small tumor size (<2 cm in diameter), nometastasis of lymph node, and at T1 stage than in cases of poor differentiation, with larger tumor size (≥2 cm in diameter), with metastasis of lymph node, and at T3 or T4 stage (P < 0.05 or P < 0.01).