CYP3A5 and epilepsy: Analyzing the distribution of CYP3A5 alleles in the groups of patients with epilepsy, as well as in control group, we found statistically significant more frequent occurrences of homozygotes of CYP3A5*3/*3 than heterozygotes of CYP3A5*1/*3 (Table 1), (Figure 1(b)).