Similarly, the association between iNOS (CCTTT)n polymorphism and asbestosis was modified by CAT –262 C > T polymorphism (Tables 3 and 4), where a higher risk of asbestosis for the iNOS LL genotype versus the combined SL and SS genotypes was also observed only among those who had CAT −262 TT genotype (OR = 5.14, P = 0.000) (Table 3). This evidence concerns the gene NOS2 and asbestosis.