MS4A4E and Alzheimer disease: Membrane-spanning 4 domains, subfamily A, member 6A (MS4A6A) and membrane-spanning 4 domains, subfamily A, member 4E (MS4A4E) were recently identified as AD risk loci with rs610932 (MS4A6A) and rs670139 (MS4A4E) showing association with AD [71, 86, 102].