Laboratory tests showed increased inflammatory markers [erythrocyte sedimentation rate (ESR): 72 mm, C-reactive protein (CRP): 28.9 mg/L], leukocytosis (WBC: 16.500 K/μL), thrombocytosis (PLT: 533.000 K/μL), positive rheumatoid factor (RF) [RF: 39.4 IU/mL (>20 IU/mL, positive)], IgG: 3.980 mg/dL, positive cytoplasmic ANCA (c-ANCA), at a titer 1/320, and PR-3 ANCA antibodies [PR-3 ANCA: 24.08 U/mL (>8 U/mL, positive)], and normal renal function tests (serum creatinine: 1.0 mg/dL, serum urea nitrogen: 35 mg/dL). The gene discussed is PRTN3; the disease is Thrombocytosis.