There was prompt resolution of all symptoms, with remaining mild sensorineural hearing loss of the left ear, improvement of abnormal laboratory tests (reduction of inflammatory markers to normal level and resolution of thrombocytosis in the 1st month, and negativity of positive c-ANCA and PR-3 ANCA antibodies in the 6th month), and moderate resolution of pachymeningitis on repeated brain MRI. This evidence concerns the gene PRTN3 and thrombocytosis disease.