CD44 and breast cancer: Moreover, CD44+CD24low+ cells in both MDA-MB-231 and DT-22 showed greater motility and invasion, and preferential expression of gene profiles observed in breast cancers metastatic to lung (Minn et al, 2005) or brain (Bos et al, 2009) and that characterize bone metastasis (Kang et al, 2003).