Intriguingly, our data suggested that AR silencing-mediated CCL2 induction resulted in enhanced PCa migration/invasion, but AR silencing via siAR also reduced PCa cells growth, which is not in agreement with an early study showing CCL2 is a potent inducer of PCa cell proliferation (Loberg et al, 2006). The gene discussed is CCL2; the disease is posterior cortical atrophy.