A NOD/SCID mouse model of local disease was used in which CHLA-255-Fluc neuroblastoma cells (106) were co-injected with PBMC (0.25 × 106) in 25 % (v/v) BD MatrigelTM Matrix Growth Factor Reduced, which includes TGFβ1. The gene discussed is TGFB1; the disease is neuroblastoma.