In this study, we measured the expression of PCAF in 5 kinds of HCC cell lines and found PCAF expression was relative low in 4 kinds of HCC cells (HepG2, Huh7, PLC/PRF/5, and SKHep1), which indicates that there is limited expression of PCAF in most of HCC cell lines and is consistent with our previous results. The gene discussed is KAT2B; the disease is hepatocellular carcinoma.