Treatment of another colon cancer cell line RKO WT and Exn5/Exn5 cells with 500 ng/ml of Tm (p= 0.05 n=3) and 500 ng/ml of Bfa (p=0.01 n=3) for 24 h also exhibited reduced levels of cell death in the DICER hypomorphic cells, which was not found upon induction of cell death with Etop or Sts (Figure S1). The gene discussed is MCL1; the disease is malignant colon neoplasm.