PALB2 and breast cancer: In multiple-breast cancer case families, germline PALB2 mutations have been reported in 1.1% (10 out of 920), 2.7% (3 out of 113), 2.0% (1 out of 50), and 0.6% (5 out of 779) of Western European families in the United Kingdom, Finland, French-Canada, and Australasian, respectively [3–6].