TCF7L2 and myeloid sarcoma: In early MS lesions the majority of TCF7L2-positive cells were found in the PPWM (36 +/- 8 cells/mm2) and remyelinating lesion areas (34 +/- 15 cells/mm2) whereas fewer cells were counted in actively demyelinating and demyelinated lesions areas (2.4 +/- 1.2 and 3.9 +/- 2.1 cells/mm2) (Figure 5A).