These various effects provide a evidence to suggest a role of IP-10 in pulmonary infectious disease including reduced IP-10 after antibiotic treatment in a murine model of Mycoplasma pneumoniae [26], use as a marker of acute tuberculous infection [27], and enhanced susceptibility to Legionellapneumophilia pneumonia in subjects with impaired IP-10 production [28]. This evidence concerns the gene CXCL10 and pneumonia.