CFTR and cystic fibrosis: IP-10 levels of airway monolayers derived from CF mice (CFTR -/-) were mildly increased at baseline (93 ± 46 pg/mL, N=10), and had a similar increase following immune stimulation (1001 ± 299 pg/mL, N=10, P<0.001 for PAO-1 and 1268 ± 112 pg/mL, N=10, P<0.001 for LPS versus vehicle control specimen; Figure 3).