Interestingly, when leukemia-free time was estimated within a specific time frame of 3-years (i.e. only the patients diagnosed in the years 2008, 2009 and 2010 were included in the analysis), a significant correlation appeared to exist between high IRF4 expression and relapse (p = 0.03) (Figure 2, I). Here, IRF4 is linked to leukemia.