TAAR1 and melanoma: Figure 5 indicates that the addition of iRGD to the C-terminus of Tα1 generally enhanced its basal antiproliferative activity in general. As shown in Figure 5A,cell growth was inhibited in a dose-dependent manner when the B16F10 melanoma cells were treated with various doses of Tα1 or Tα1-iRGD (0.03125 μmol/mL to 0.5000 μmol/mL).