BCL2 and B-cell chronic lymphocytic leukemia: Previous studies showed that BCL2 −938CC (rs2279115) genotype were associated with poor prognosis for renal cancer [27] for SCLC patients [28], but with favorable survival for patients with chronic lymphocytic leukemia [29] and B large lymphoma [30], while the +21AA (rs1801018) genotype had a significantly longer survival time in acute myeloid leukemia [31].