TLR5 and Salmonella Infections: Similar to WT Salmonella infection (Fig. 1 E), TLR5−/− mice also had lower bacterial burden in the cecum compared to WT mice (Fig. 8 A), consistent with our previous finding that TLR5 promotes cecal colonization of Salmonella. The ceca of all mice were inflamed, small and pale (Fig. S1 D).