Regarding for the association between FTO gene and CVD risk, Doney et al. [8] firstly demonstrated that the A allele of rs9939609 in the FTO gene increased the risk of myocardial infarction in 4,897 patients with T2D in the prospective study, which was independently of BMI, glycohemoglobin, mean arterial pressure, HDL-C, triglycerides, and total cholesterol. Here, FTO is linked to type 2 diabetes mellitus.