PEMT and metabolic dysfunction-associated steatotic liver disease: While it is well known that environmental risk factors influence the development and progression of NAFLD [16]–[17], the contribution of the individual genetic variation to disease predisposition remains uncertain, despite the fact that several genes, including PPARα, phosphatidyl ethanolamine methyltransferase (PEMT), and Patatin like phospholipase-3 (PNPLA3), have been suggested as potential candidates for either NAFLD susceptibility or disease progression [18]–[21].