Interestingly, upon ectopic expression of TRPC6 cDNA in cancer cells, where intracellular calcium was quenched through TMB-8 treatment, the gene expression pattern was altered and the expressions of the genes involved in cellular apoptosis was consistently low (Figure 4b (lane 17, 18, 19, 20, 22 & 24)). The gene discussed is TRPC6; the disease is cancer.