A subset of patients with eosinophilic esophagitis responds to acid suppressive therapy, indicating some overlap between eosinophilic esophagitis and gastroesophageal reflux disease [6]; this is now considered as a separate entity labelled “proton pump inhibitors (PPI) responsive oesophageal eosinophilia” [13] In children, eosinophilic esophagitis has been shown to be associated with IgE- and non-IgE-mediated food allergy, and the majority of cases respond to elemental diets or specific food protein elimination [6]. This evidence concerns the gene IGHE and food allergy.