To verify that the enhanced infection of SAMHD1Δ/Δ BMDCs was due to the absence of SAMHD1 activity, we complemented SAMHD1Δ/Δ cells by transduction with lentiviral particles encoding murine SAMHD1 or empty vector prior to infection with NL43-CMVGFP. The gene discussed is SAMHD1; the disease is infection.