We also found a significant difference between hOGG1 Ser326Cys genotype and lung cancer susceptibility in studies with hospital-based controls for homozygote model (OR = 0.798; 95% CI = 0.649–0.982; Pheterogeneity = 0.007),dominant model (OR = 0.122; 95% CI = 0.091–0.163; Pheterogeneity = 0.000). The gene discussed is OGG1; the disease is lung carcinoma.