The set of genes more prognostic than PGR in ER+ breast cancer was highly enriched for genes associated with proliferation and cell cycle (for example, 12% of this set of genes was associated with the GO term mitotic cell cycle, false discovery rate (FDR) for enrichment = 3.4e-32), including the highly ranked gene AURKA (adjusted P-value <2.4e-13). This evidence concerns the gene AURKA and breast carcinoma.